سامانه همایش های موسسه پژوهشی علوم و صنایع غذایی

صفحه اصلی / سومین همایش ملی پژوهش های کاربردی امنیت غذایی: فرآوری، ایمنی و سلامت

Antidiabetic Potential of Cactus Fruit(Opuntia spp.): Bioactive Compounds, Mechanisms, and Applications in Functional Foods

نویسندگان :

Samaneh Pishdad¹

1- دانشگاه آزاد اسلامی واحد نجف آباد

کلمات کلیدی :

Diabetes Mellitus،Cactus Fruit،Opuntia،Phytotherapy،Glycemic Control،Bioactive Compounds

چکیده :

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia, resulting from defects in insulin secretion, insulin action, or both. The global prevalence of diabetes is alarmingly high, necessitating the exploration of novel and effective therapeutic strategies. Cactus fruit, particularly from the Opuntia genus, has garnered significant attention for its rich phytochemical profile and promising antidiabetic properties. This review consolidates current scientific evidence on the antidiabetic potential of cactus fruit, focusing on its bioactive compounds, mechanisms of action, and outcomes from preclinical and clinical studies. The soluble fiber, polyphenols, flavonoids, and betalains present in cactus fruit contribute to glucose regulation by slowing carbohydrate absorption, enhancing insulin sensitivity, and protecting pancreatic β-cells. Clinical trials have demonstrated the efficacy of Opuntia fruit and its extracts in improving glycemic control markers such as postprandial glucose, fasting blood glucose, and HbA1c. Further research is warranted to optimize its therapeutic application and understand its long-term effects in managing diabetes.